Membrane Interacting Regions of Dengue Virus NS2A Protein

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Membrane Interacting Regions of Dengue Virus NS2A Protein

The Dengue virus (DENV) NS2A protein, essential for viral replication, is a poorly characterized membrane protein. NS2A displays both protein/protein and membrane/protein interactions, yet neither its functions in the viral cycle nor its active regions are known with certainty. To highlight the different membrane-active regions of NS2A, we characterized the effects of peptides derived from a pe...

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ژورنال

عنوان ژورنال: The Journal of Physical Chemistry B

سال: 2014

ISSN: 1520-6106,1520-5207

DOI: 10.1021/jp504911r